Signe was born in Latvia. She studied Philosophy at Moscow State University for 5 years. Seeking a challenge, Signe moved to New York where she worked for independent animator Bill Plympton in capacity of cel painter, art director and production manager. In 1998, Signe received her US green card as ´extraordinary ability alien´. From 1998 on, she made her films at her own studio. In 2005 she became a NYFA Fellow in Film. Signe has written, directed and animated 15 shorts and one feature film. Collectively, they’ve been accepted in over 300 film festivals around the world and received many awards. She was also awarded a prestigious Guggenheim Fellowship in 2017. Signe is currently working on her second animated feature, titled "My Love Affair With Marriage", which will use music and science to examine the biological chemistry of love and gender, as well as the societal pressures on an individual to conform to social mores.